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Tirzepatide 
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What Is Tirzepatide

Tirzepatide is GLP-1/GIP medication synthetically produced as a treatment for people with Type 2 diabetes. Known as a “twincretin,” Tirzepatide is the first and only dual glucagon-like peptide (GLP-1) and glucose-dependent insulinotropic peptide (GIP) receptor agonist that utilizes the effects of the GLP and GIP incretin hormones to help manage insulin release and lower blood sugar levels. Thanks to this process, patients can eliminate a substantial amount of excess body fat by using Tirzepatide for weight loss.

How Does Tirzepatide Work for Weight Loss?

In terms of weight loss treatment, Tirzepatide has a unique mechanism of action. However, to help you understand how Tirzepatide helps with weight loss, we’ll need to start by explaining the significance of GLP and GIP hormones to the human body.

Step
GLP

The glucagon-like peptide (GLP) is a naturally occurring incretin hormone released from various areas of the body, such as the stomach and central nervous system (CNS), to stimulate insulin release from the pancreas after food consumption. In addition to stimulating insulin release, the GLP hormone also inhibits glucagon secretion, which further helps to reduce glucose levels.
As all of this occurs, the GLP hormone also inhibits gastric acid secretion, which can slow down gastric emptying in the stomach and help reduce your appetite.

Step
GIP

Then there’s the glucose-dependent insulinotropic peptide hormone or GIP. Typically, soon after the GLP hormone is released, the GIP hormone is also released from the enteroendocrine cells of the small intestine during the start of digestion also to further assist the GLP hormone in promoting insulin secretion and regulating blood sugar levels in the body. However, the role of the GIP hormone doesn’t stop there. The hormone also stimulates lipolysis–the breakdown of fats and triglycerides into energy–and can target the CNS to inhibit your calorie intake, which can also make it easier to reduce body weight.

Step
GLP-1 and GIP

To utilize these metabolic and digestive effects for weight loss, pharmaceutical manufacturers synthetically engineer drugs known as receptor agonists to mimic the actions of the GLP and GIP certain hormones, thus the creation of GLP-1 and GIP receptor agonist medications.

Step
Insulin secretion

By combining these two drugs, science has created the first ever GIP/GLP-1 dual receptor agonist, which Tirzepatide uses to create a synergistic effect to enhance the stimulation of insulin secretion, gastric emptying, and glycemic control on a more advanced scale than Ozempic and Wegovy. To help maintain this process consistently to produce the desired results, Tirzepatide is administered via subcutaneous injection once weekly, allowing it to work effectively as a treatment for both weight loss and diabetes.

Before & After

Andy T.

I started the Tirzepatide Weight Loss Program with Slim Clinic a year ago. Dr. Jacquemin is an expert in both of these fields and fine tuned my program to produce incredible results. At 43 years old with 3 kids and a heavy workload, it was hard to stay in shape, and as life got busier my physique went downhill. Thanks to the staff at Slim Clinic and Dr Jacquemin, I am in the best shape of my life, have energy like I did 20 years ago and I feel incredible. If you want a life changing transformation, clinically supervised, that is both safe and effective, Slim Clinic is the only option. I cannot recommend this organization highly enough.

I started the Tirzepatide Weight Loss Program with Slim Clinic a year ago. Dr. Jacquemin is an expert in both of these fields and fine tuned my program to produce incredible results. At 43 years old with 3 kids and a heavy workload, it was hard to stay in shape, and as life got busier my physique went downhill. Thanks to the staff at Slim Clinic and Dr Jacquemin, I am in the best shape of my life, have energy like I did 20 years ago and I feel incredible. If you want a life changing transformation, clinically supervised, that is both safe and effective, Slim Clinic is the only option. I cannot recommend this organization highly enough.

Andy T.

I started the Tirzepatide Weight Loss Program with Slim Clinic a year ago. Dr. Jacquemin is an expert in both of these fields and fine tuned my program to produce incredible results. At 43 years old with 3 kids and a heavy workload, it was hard to stay in shape, and as life got busier my physique went downhill. Thanks to the staff at Slim Clinic and Dr Jacquemin, I am in the best shape of my life, have energy like I did 20 years ago and I feel incredible. If you want a life changing transformation, clinically supervised, that is both safe and effective, Slim Clinic is the only option. I cannot recommend this organization highly enough.

Tirzepatide 
Timeframe
1 year
Results
lost 295 Lbs
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How quickly will I see results

Because every patient has a unique physiology, the weight loss results achieved with Tirzepatide will vary depending on the nature of each case.

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How To Take

Where to administer 

Tirzepatide comes in the form of a multiple dose injectable vial that you can inject subcutaneously into the stomach, thighs, or the back of your upper arms. As a precaution, it is recommended that you rotate the areas chosen for each injection. This can help you to avoid experiencing redness and irritation at the injection site.

How often

You can choose any day of the week, whatever is most convenient for you. However, once you’ve chosen a specific time frame, you must commit to administering the medicine on the same day every week for consistency. If, at any point, you decide to change the day you would typically take your dose, you will need to allow 72 hours to pass before taking your next dose to recalibrate your dosing schedule.

If you missed a dose

If you miss a dose, try to take it as soon as you remember. You’ll have four days (96 hours) to administer the missed dose before your next scheduled dose. However, if it’s been more than four days, skip the missed dose and take your next dose on the regularly scheduled day. Also, try to avoid taking two doses within three days of each other. This can help reduce the risk of double dosing, which can cause further complications.

Where Can I Get Tirzepatide To Lose Weight?

Tirzepatide is only available with a prescription, which you can only obtain from a licensed healthcare provider. They can evaluate your medical history, assess your current health status, and determine whether the medication is appropriate for you. In these cases, it’s usually best to receive your prescription from an established and reputable weight loss clinic that can help you use the medicine effectively as a weight loss treatment.

If you’re struggling with weight management, the staff at The Slim Weight Loss Clinic can provide several weight loss solutions, such as Tirzepatide, to help you achieve your weight loss goals. Contact us at 1-866-776-9658 to schedule an appointment at any of our weight loss clinics in the United States to learn more about using Tirzepatide for weight loss.

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Who Shouldn’t Take Tirzepatide?

Who Shouldn’t Take Tirzepatide?

Although Tirzepatide can help treat Type 2 diabetics, it should not be used as a treatment for people with Type 1 diabetes. Like most prescription medications, Tirzepatide contains other ingredients that can cause some patients to experience allergic reactions, so you may need to avoid using the medicine if you suddenly break out in a rash or have trouble breathing after starting treatment. Tirzepatide may also cause or even worsen other serious health complications, so your healthcare provider may recommend that you avoid using the medication if you suffer from pre-existing medical conditions such as:

  • Gallbladder issues such as gallstones
  • Pancreatitis
  • Kidney complications such as acute kidney failure
  • Gastrointestinal disease
  • Diabetic retinopathy
  • Type 2 Multiple Endocrine Neoplasia syndrome (MEN2)

Tirzepatide may also increase the risks of thyroid tumors, so your healthcare provider may recommend that you avoid using the treatment if you or other family members have a history of thyroid cancer. Make sure to discuss your full medical history and any allergies you may have with your doctor so they can weigh the risks and the benefits of using the medication to determine whether Tirzepatide will work as a viable weight loss treatment for you.
Women who are pregnant or breastfeeding should also avoid using Tirzepatide as the medicine may harm the unborn fetus or pass through the breastmilk and negatively affect newborns. Naturally, always inform your physician of sudden life changes, such as an unexpected pregnancy, before or during Tirzepatide. They can help you safely discontinue the medication so you can remain healthy and free of complications as you prepare to give birth.

Possible Side Effects

Because Tirzepatide alters how the digestive system processes food, you may experience various stomach-related side effects during the first few weeks of treatment. The most common issues that patients commonly report include:

  • Diarrhea
  • Nausea
  • Vomiting
  • Stomach pain
  • Constipation
  • Lack of appetite
  • Heartburn
  • Gastroparesis

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Author

Thierry Jacquemin

Dr. Thierry Jacquemin is an international board-certified…

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Resources
  1. The ‘King Kong’ of Weight-Loss Drugs is Coming
  2. Tirzepatide Once Weekly for the Treatment of Obesity
  3. Tirzepatide Injection
  4. Tirzepatide, a New Era of Dual-Targeted Treatment for Diabetes and Obesity: A Mini-Review:
  5. Can Tirzepatide Help You Lose Weight?

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Dr. Thierry Jacquemin

Dr. Thierry Jacquemin is an international board-certified…

Dr. Gary T. Marshall

Dr. Gary T. Marshall, MD, FACS practices in the New York City…

Dr. Gary Kawesch

Dr. Gary Kawesch, MD, FACS practices in the Los Angeles…

Dr. Thierry Jacquemin

Dr. Thierry Jacquemin is an international board-certified…